SYRE

Spyre Therapeutics Inc

Latest period2026 - Q1Total superinvestors199

Top 10 Superinvestors by Shares Owned

This chart shows the top 10 superinvestors based on the number of shares they owned in 2025-Q4 and 2026-Q1. According to the most recent SEC 13F filing, 199 superinvestors own shares of Spyre Therapeutics Inc (SYRE), although recent data may remain incomplete due to pending filings.

Quarter-over-Quarter Change (%)

This chart highlights the quarter-over-quarter change (%) in the number of superinvestors holding Spyre Therapeutics Inc (SYRE), the total shares they held, and the total reported dollar value. It gives a clear view of whether there is ongoing momentum. The dotted lines at the top and bottom adjust longer bars to keep smaller data points visible for better comparison.

Superinvestors' Activity (%) Over the Last 4 Quarters

This chart shows superinvestors' activity with Spyre Therapeutics Inc (SYRE) over the last four quarters, highlighting the percentage of investors who added, increased, decreased, held, or exited their positions, revealing shifts in sentiment over time.

Superinvestors' Past Actions

This chart displays superinvestors' past actions with Spyre Therapeutics Inc (SYRE) over the last 10 years (40 quarters), helping to visualize the collective momentum and investment trends over time.

Superinvestors ownership

SuperinvestorPortfolio %Reported Value
Stephanie J. Brown@Fmr Llc
Recent Activity
Increased 1.23%
0.04%
$594.235M
11.781M shares@ 50.45 avg price
Spencer Fleming@Blackrock, Inc.
Recent Activity
Decreased -0.01%
0.01%
$278.49M
5.521M shares@ 50.44 avg price
Roderick Wong@Rtw Investments, Lp
Recent Activity
2.1%
$210.435M
4.172M shares@ 50.44 avg price
Erin O'Connor@Fairmount Funds Management Llc
Recent Activity
14.65%
$202.673M
4.018M shares@ 50.44 avg price
Joseph Edelman@Perceptive Advisors Llc
Recent Activity
Increased 23.27%
3.73%
$190.826M
3.783M shares@ 50.44 avg price
Sherman G. Souther@Venrock Adviser, Llc
Recent Activity
6.94%
$185.894M
3.685M shares@ 50.44 avg price
Christine M. Buchanan@Vanguard Capital Management Llc
Recent Activity
New Position
0.01%
$154.215M
3.057M shares@ 50.44 avg price
Janet McWilliams@Driehaus Capital Management Llc
Recent Activity
Decreased -3.17%
1.04%
$140.767M
2.791M shares@ 50.44 avg price
ELIZABETH SCHAEFER@State Street Corp
Recent Activity
Increased 15.22%
0.01%
$131.499M
2.607M shares@ 50.45 avg price
David Kim@Paradigm Biocapital Advisors Lp
Recent Activity
Increased 33.4%
2.02%
$98.724M
1.957M shares@ 50.44 avg price

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