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James Silverman

Opaleye Management Inc.

Assets Managed
$759.221M
Holdings
54
Last Quarter
2026 - Q1
Filed Date
11d ago
Growth Rate
0.18%(2Q avg: 3.67%)
Sustained Growth
4 quarters

Portfolio positions

This chart displays the top 10 holdings in Opaleye Management Inc.'s 2026 - Q1 portfolio, based on their 13F SEC filing, out of a total of 54 positions.

Assets under management

The assets under management (AUM) of Opaleye Management Inc. over the past 10 years (40 quarters) show continuous growth in total asset value over the last 4 quarters. As of the latest 13F SEC filing for 2026 - Q1, they manage 759.221M in assets, with a quarterly growth rate of 0.18% and a 2-quarter average growth rate of 3.67%. The portfolio is managed by James Silverman, and others.

Portfolio holdings

InvestmentPortfolio %Reported Value
HROW
Harrow Inc
Recent Activity
Decreased -27.47%
13.16%
$99.864M
2.832M shares@ $35.27 avg price
LQDA
Liquidia Corp
Recent Activity
Increased 4.52%
11.7%
$88.82M
2.545M shares@ $34.9 avg price
ETON
Eton Pharmaceuticals Inc
Recent Activity
9.3%
$70.585M
2.86M shares@ $24.68 avg price
SLGL
Sol-gel Technologies Ltd
Recent Activity
Increased 10.2%
5.22%
$39.61M
500,000 shares@ $79.22 avg price
RYTM
Rhythm Pharmaceuticals Inc
Recent Activity
Decreased -62.72%
4.66%
$35.323M
123,000 shares@ $287.19 avg price
APGE
Apogee Therapeutics Inc
Recent Activity
Increased 0.45%
4.33%
$32.826M
390,000 shares@ $84.17 avg price
IRON
Disc Medicine Inc
Recent Activity
Increased 110.5%
3.55%
$26.919M
421,000 shares@ $63.94 avg price
URGN
Urogen Pharma Ltd
Recent Activity
Increased 432.75%
3.39%
$25.711M
1.43M shares@ $17.98 avg price
CBIO
Crescent Biopharma Inc
Recent Activity
Increased 11.4%
3.18%
$24.113M
1.313M shares@ $18.38 avg price
STOK
Stoke Therapeutics Inc
Recent Activity
Increased 0.72%
3.01%
$22.792M
700,000 shares@ $32.56 avg price

1-10 of 54