Raymond Debbane

Siren, L.l.c.

Assets Managed

$3.607B

Holdings

100

Last Quarter

2026 - Q1

Filed Date

1mo 5d ago

Growth Rate

7.61%(2Q avg: 19.38%)

Sustained Growth

4 quarters

Portfolio positions

This chart displays the top 10 holdings in Siren, L.l.c.'s 2026 - Q1 portfolio, based on their 13F SEC filing, out of a total of 100 positions.

Assets under management

The assets under management (AUM) of Siren, L.l.c. over the past 10 years (40 quarters) show continuous growth in total asset value over the last 4 quarters. As of the latest 13F SEC filing for 2026 - Q1, they manage 3.607B in assets, with a quarterly growth rate of 7.61% and a 2-quarter average growth rate of 19.38%. The portfolio is managed by Raymond Debbane, and others.

Portfolio holdings

Investment	Portfolio %	Reported Value	Recent Activity
SRRK Scholar Rock Holding Corp Recent Activity	14.76%	$532.158M 10.825M shares@ $49.16 avg price
KYMR Kymera Therapeutics Inc Recent Activity Decreased -3.04%	7.36%	$265.431M 3.187M shares@ $83.3 avg price	Decreased -3.04%
ERAS Erasca Inc Recent Activity Increased 28.4%	5.05%	$181.932M 11.244M shares@ $16.18 avg price	Increased 28.4%
EWTX Edgewise Therapeutics Inc Recent Activity Decreased -2.2%	3.87%	$139.553M 4.43M shares@ $31.51 avg price	Decreased -2.2%
BGNE Beigene Ltd-adr Recent Activity Decreased -7%	3.83%	$138.091M 465,000 shares@ $296.97 avg price	Decreased -7%
TNGX Tango Therapeutics Inc Recent Activity Decreased -30.71%	3.29%	$118.347M 5.657M shares@ $20.93 avg price	Decreased -30.71%
BCAX Bicara Therapeutics Inc Recent Activity Increased 11.24%	3.2%	$115.421M 5.803M shares@ $19.89 avg price	Increased 11.24%
RVMD Revolution Medicines Inc Recent Activity Decreased -16.78%	3%	$108.043M 1.111M shares@ $97.25 avg price	Decreased -16.78%
ARWR Arrowhead Pharmaceuticals In Recent Activity Increased 7.67%	2.81%	$101.29M 1.615M shares@ $62.7 avg price	Increased 7.67%
MANE Veradermics Inc Recent Activity New Position	2.64%	$95.064M 1.505M shares@ $63.15 avg price	New Position

1-10 of 100